The three major challenges cops face in the hunt for Savannah Guthrie's kidnapped mother Nancy, 84

The massive manhunt for Nancy Guthrie has entered its fifth day as police face increasing challenges to locate Today Show host Savannah Guthrie's elderly mother. 

Despite extensive resources funneled to Nancy's community in Catalina Foothills, Arizona, authorities are still struggling to come up with answers. Their work has been made more complicated by the victim's age and health status, limited security footage due to the remote area, and enhanced media attention. 

Nancy, 84, was reported missing on Sunday afternoon by family members after she missed her weekly church service. 

She was last seen at her Tucson home, where she lives alone, on Saturday afternoon. 

Her disappearance spiraled into an unbelievable nightmare when authorities began to investigate the case as a kidnapping. 

Blood was found in her home, and her Ring camera had been removed. Several media outlets, including local Arizona stations and TMZ, also reported receiving unverified ransom notes. 

Prima County Sheriff Chris Nanos hasn't confirmed the validity of the ransom notes, but told reporters that the department believes Nancy was 'taken from her home against her will.' 

As the sheriff's office and the FBI continue investigating Nancy's disappearance, the Daily Mail explores the major challenges they face below.

Nancy Guthrie, pictured above with Savannah in 2021, was last seen on Saturday night and has been missing for five days 

Nancy's shock disappearance has generated increased media attention due to her daughter Savannah's broadcast career. The two are pictured here together on set 

Authorities believe Nancy was taken from her home. Savannah and her siblings, Annie and Camron, released a video on Wednesday night pleading for their mother's return 

Nanos told reporters during a press conference on Tuesday that one of law enforcement's top concerns was Nancy's age and health. 

Authorities said Nancy takes critical prescription medication that she needs to survive. 

As former FBI Supervisory Special Agent and Crisis Negotiator Jason Pack wrote in the Daily Mail: 'In the search for an 84-year-old woman with serious health issues who needs daily medication, every hour matters.' 

Read More The Nancy Guthrie crime scene clue that's most chilling of all: FBI Special Agent JASON PACK

Savannah and her siblings, Annie and Camron, released a video on Wednesday evening pleading with their mother's alleged kidnapper to communicate with them. 

'She is 84 years old. Her health, her heart is fragile. She lives in constant pain. And she is without any medicine. She needs it to survive. She needs it not to suffer,' Savannah tearfully said in the video. 

A journalist noted during Tuesday's press conference that Nancy needed her medication every day and asked Nanos whether law enforcement was looking for someone who is still alive. 

'We hope we are,' Nanos responded. 

Nancy also has a pacemaker, which generates electric pulses to help her heart beat. Authorities confirmed at a press conference on Thursday that the device last sent data to her Apple Watch around 2am on Sunday. 

'This is day four or five and we don't know if she's getting her medication, and that in itself could prove fatal,' Nanos said during the press conference. 

Authorities have been met with many challenges in the case, including Nancy's age and health, the secluded area where she was allegedly taken, and increased media attention. Nancy and Savannah are pictured here in 2023 on the set of the Today Show 

Nancy's home in Catalina Foothills is in a secluded, rural area of Tucson. The sprawling property has a driveway far from the street, making it difficult to capture Ring Camera footage from neighboring homes. 

Authorities have pleaded with the public to share any relevant security camera footage that could help with the search. 

'In addition to neighbors' videos, officers will be culling footage from traffic cameras on nearby roads, business security cameras, ATMs and gas station cameras,' Pack said. 

'The fact that Sheriff Nanos is publicly pleading for video tells me they don't have the smoking gun footage yet.'

The secluded environment also makes it more difficult for law enforcement officials to search the surrounding area for Nancy. 

The FBI announced during a press conference on Thursday that they were offering a reward of up to $50,000 for information leading to Nancy's recovery and/or the arrest and conviction of anyone involved in her disappearance. 

Authorities believe Nancy was taken from her home sometime late Saturday or early Sunday. Pictured here is Nancy's secluded Arizona home 

Nancy's home doesn't have any close neighbors where Ring Camera footage could clearly capture what happened when she disappeared 

Authorities said a Ring Camera outside of Nancy's home had been removed and there was blood found  

Savannah's high-profile job as a broadcast journalist on NBC has drawn increased media attention to Nancy's disappearance. 

Nanos told reporters on Tuesday that the media have been helpful in generating tips for the case, but have also posed an additional challenge. 

The sheriff said he spent hours answering media questions about Nancy, adding that it's 'not fair to the case.' 

Authorities haven't yet indicated a motive for the kidnapping, but media outlets have reported receiving ransom notes. 

Mary Coleman, a news anchor for local Arizona outlet KOLD, told CNN on Wednesday that the alleged ransom note they received included information only a captor would know. 

Prima County Sheriff Chris Nanos said during a press conference that the increased media attention has been helpful, but also presented a challenge 

'It also included a dollar amount, a deadline, and, again, other specifics that only Guthrie's abductor might know, so that definitely raised some red flags,' Coleman added. 

TMZ also reported receiving a ransom note demanding millions in Bitcoin for Nancy's release. 

FBI Special Agent Heith Janke said on Thursday that authorities have made one arrest for an imposter ransom demand.  

Janke then issued a direct message to Nancy's abductors. 'You still have the time to do the right thing before this becomes a worse, much worse scenario for you. Please return Nancy home,' he said.